Search results for "organic bioelectronics"

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Current-Driven Organic Electrochemical Transistors for Monitoring Cell Layer Integrity with Enhanced Sensitivity

2021

In this progress report an overview is given on the use of the organic electrochemical transistor (OECT) as a biosensor for impedance sensing of cell layers. The transient OECT current can be used to detect changes in the impedance of the cell layer, as shown by Jimison et al. To circumvent the application of a high gate bias and preventing electrolysis of the electrolyte, in case of small impedance variations, an alternative measuring technique based on an OECT in a current-driven configuration is developed. The ion-sensitivity is larger than 1200 mV V-1 dec-1 at low operating voltage. It can be even further enhanced using an OECT based complementary amplifier, which consists of a p-type a…

Materials scienceTransistors ElectronicBiomedical EngineeringPharmaceutical ScienceElectrolyteBiosensing TechniquesTransistorslaw.inventionBiomaterialsElectrolytesPEDOT:PSSimpedance sensinglawcell layer integrityElectric ImpedanceElectronicPEDOT:PSSHumansElectrical impedanceorganic bioelectronicsElectrolysisbusiness.industryAmplifierTransistorcell layer integrity; impedance sensing; organic bioelectronics; organic electro-chemical transistors; PEDOT:PSS; Caco-2 Cells; Electric Impedance; Electrolytes; Humans; Biosensing Techniques; Transistors ElectronicOptoelectronicsCaco-2 Cellsbusinessorganic electro-chemical transistorsBiosensorOrganic electrochemical transistor
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